Link: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2821348
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Key Points
Question What is the colorectal cancer mortality benefit of screening with fecal immunochemical tests (FITs)?
Findings In this nested case control study of 10 711 individuals, completing a FIT to screen for colorectal cancer was associated with a reduction in risk of dying from colorectal cancer of approximately 33% overall, and there was a 42% lower risk for left colon and rectum cancers. FIT screening was also associated with lower risk of colorectal cancer death among non-Hispanic Asian, non-Hispanic Black, and non-Hispanic White people.
Meaning This study provides US community-based evidence that suggests FIT screening lowers the risk of dying from colorectal cancer and supports the strategy of population-based screening using FIT.
Author(s): Chyke A. Doubeni, MD, MPH1,2; Douglas A. Corley, MD, PhD3; Christopher D. Jensen, PhD3; et al
Publication Date: July 19, 2024
Publication Site: JAMA Netw Open.
2024;7(7):e2423671.
doi:10.1001/jamanetworkopen.2024.23671